homefeedbacksupportlog on 7-Jan-2009 
  About F1000

 What is F1000 Biology?
 Key features
 How it's organized
 FAQs
 Faculties and sections
 Scope of sections
 List of Faculty Members
 The evaluation system
 Citing F1000
 Take a tour of the site
 Accessing fulltexts
 PubMed linkout
 How to subscribe
 Academic subscriptions
 Corporate subscriptions
 Try F1000 for free
 Who we are
 Media information
 Librarian resources
 Press releases
 In the press
 Developing countries
 F1000 Medicine
 Terms and conditions
 Privacy policy
 Contact us


Colin Watts
Wellcome Trust Biocentre, University of Dundee, Dundee, United Kingdom

Faculty Member: Immunology > Antigen Processing & Recognition [ since 4 July 2001 ]
[ Evaluations ]
to email [Help]
Evaluations

Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9.
Park B, Brinkmann MM, …, Kim YM, Ploegh HL
Nat Immunol 2008 Dec 9(12):1407-14 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Colin Watts with Michele West
Evaluated 2 Jan 2009

Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance.
Nedjic J, Aichinger M, …, Mizushima N, Klein L
Nature 2008 Sep 18 455(7211):396-400 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Vojo Deretic / Edward Collins / Thomas Hunig / Colin Watts with Michele A.West
Evaluated 17 Oct 2008

Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis.
Asagiri M, Hirai T, …, Saftig P, Takayanagi H
Science 2008 Feb 1 319(5863):624-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Grant McFadden / Colin Watts / Robert Booth / Lionel Ivashkiv
Evaluated 5 Feb 2008


Anti-inflammatory activity of human IgG4 antibodies by dynamic Fab arm exchange.
van der Neut Kolfschoten M, Schuurman J, …, Aalberse RC, Parren PW
Science 2007 Sep 14 317(5844):1554-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Colin Watts / Thomas Hunig
Evaluated 27 Sep 2007


Distinct pathways of antigen uptake and intracellular routing in CD4 and CD8 T cell activation.
Burgdorf S, Kautz A, …, Knolle PA, Kurts C
Science 2007 Apr 27 316(5824):612-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Eric Denkers / Christian Engwerda / Colin Watts / Elizabeth Mellins
Evaluated 9 May 2007

Functional epistasis on a common MHC haplotype associated with multiple sclerosis.
Gregersen JW, Kranc KR, …, Bell JI, Fugger L
Nature 2006 Oct 5 443(7111):574-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Angela Vincent / Colin Watts
Evaluated 24 Oct 2006

NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells.
Savina A, Jancic C, …, Raposo G, Amigorena S
Cell 2006 Jul 14 126(1):205-18 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Colin Watts / Clifford Harding / Shiv Pillai / Peter Van Endert / Philippe Pierre / Ann Hill
Evaluated 1 Aug 2006

Cell surface recycling of internalized antigen permits dendritic cell priming of B cells.
Bergtold A, Desai DD, Gavhane A, Clynes R
Immunity 2005 Nov 23(5):503-14 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Dan Conrad / Shiv Pillai / Colin Watts / Michael Gold
Evaluated 12 Dec 2005

Quantitative and dynamic assessment of the contribution of the ER to phagosome formation.
Touret N, Paroutis P, …, Mellman I, Grinstein S
Cell 2005 Oct 7 123(1):157-70 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Rainer Duden / Craig Roy / Colin Watts / Clifford Harding / Ralph Isberg / Peter Van Endert / Scott Gray-Owen / Sanford Simon / Frank Momburg
Evaluated 20 Oct 2005

Important role of cathepsin S in generating peptides for TAP-independent MHC class I crosspresentation in vivo.
Shen L, Sigal LJ, Boes M, Rock KL
Immunity 2004 Aug 21(2):155-65 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Peter Van Endert / Colin Watts / Edward Collins / Frank Momburg
Evaluated 25 Aug 2004

ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells.
Guermonprez P, Saveanu L, …, Van Endert P, Amigorena S
Nature 2003 Sep 25 425(6956):397-402 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Colin Watts / Lutz Walter / Frank Momburg / Shiv Pillai / Francisco Garcia-del Portillo / Caetano Reis e Sousa / Judith Klumperman / Stefan Kaufmann / Sergio Grinstein
Evaluated 2 Oct 2003

Quantitating protein synthesis, degradation, and endogenous antigen processing.
Princiotta MF, Finzi D, …, Bennink JR, Yewdell JW
Immunity 2003 Mar 18(3):343-54 [abstract on PubMed] [related articles] [order article]
Selected by | Colin Watts / Tim Elliott
Evaluated 26 Mar 2003

Cathepsin L regulates CD4+ T cell selection independently of its effect on invariant chain: a role in the generation of positively selecting peptide ligands.
Honey K, Nakagawa T, Peters C, Rudensky A
J Exp Med 2002 May 20 195(10):1349-58 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Colin Watts
Evaluated 27 Aug 2002

Burst-enhancing role of the IgG membrane tail as a molecular determinant of memory.
Martin SW, Goodnow CC
Nat Immunol 2002 Feb 3(2):182-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Colin Watts / Toshitada Takemori / Andy Chan
Evaluated 30 Jan 2002

^Top  Back to Faculty Members


© 1999-2009 Biology Reports Ltd unless otherwise stated. < info@f1000.com >   Terms and conditions   Legal info