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Morag Young
Department of Endocrine Genetics, Prince Henry's Institute of Medical Research, Australia

Faculty Member: Physiology > Endocrinology [ since 10 March 2005 ]
[ Evaluations ]
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Evaluations

Rapid nongenomic effects of aldosterone on the renal vasculature in humans.
Schmidt BM, Sammer U, …, Delles C, Schmieder RE
Hypertension 2006 Apr 47(4):650-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Morag Young
Evaluated 29 Oct 2008

Corticosteroids and redox potential modulate spontaneous contractions in isolated rat ventricular cardiomyocytes.
Rossier MF, Lenglet S, …, Python M, Maturana A
Hypertension 2008 Oct 52(4):721-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Morag Young
Evaluated 24 Sep 2008

Deoxycorticosterone acetate-salt mice exhibit blood pressure-independent sexual dimorphism.
Karatas A, Hegner B, …, Regitz-Zagrosek V, Dragun D
Hypertension 2008 Apr 51(4):1177-83 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Morag Young
Evaluated 23 Jul 2008

Immediate mineralocorticoid receptor blockade improves myocardial infarct healing by modulation of the inflammatory response.
Fraccarollo D, Galuppo P, …, Ertl G, Bauersachs J
Hypertension 2008 Apr 51(4):905-14 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Morag Young
Evaluated 27 Mar 2008

Glucocorticoids exert opposing effects on macrophage function dependent on their concentration.
Lim HY, Müller N, …, van den Brandt J, Reichardt HM
Immunology 2007 Sep 122(1):47-53 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Morag Young
Evaluated 27 Mar 2008

Targeted skin overexpression of the mineralocorticoid receptor in mice causes epidermal atrophy, premature skin barrier formation, eye abnormalities, and alopecia.
Sainte Marie Y, Toulon A, …, Farman N, Jaisser F
Am J Pathol 2007 Sep 171(3):846-60 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Morag Young
Evaluated 26 Sep 2007

Aldosterone induces epithelial-mesenchymal transition via ROS of mitochondrial origin.
Zhang A, Jia Z, Guo X, Yang T
Am J Physiol Renal Physiol 2007 Sep 293(3):F723-31 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Morag Young
Evaluated 23 Aug 2007

Pivotal role of the mineralocorticoid receptor in corticosteroid-induced adipogenesis.
Caprio M, Fève B, …, Lombès M, Zennaro MC
FASEB J 2007 Jul 21(9):2185-94 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Morag Young
Evaluated 3 Jul 2007

Macrophages and neutrophils are the targets for immune suppression by glucocorticoids in contact allergy.
Tuckermann JP, Kleiman A, …, Schmid W, Schütz G
J Clin Invest 2007 May 117(5):1381-90 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Morag Young
Evaluated 4 May 2007

Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activity.
Leopold JA, Dam A, …, Pitt B, Loscalzo J
Nat Med 2007 Feb 13(2):189-97 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Gerardo Gamba / Morag Young / Michael Clark / Michael Frenneaux
Evaluated 30 Mar 2007


Loss of the limbic mineralocorticoid receptor impairs behavioral plasticity.
Berger S, Wolfer DP, …, Lipp HP, Schütz G
Proc Natl Acad Sci U S A 2006 Jan 3 103(1):195-200 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Megan Holmes / Achim Peters / Victor Reus / Jonathan Seckl / Morag Young
Evaluated 6 Jul 2006

Angiotensin II-dependent chronic hypertension and cardiac hypertrophy are unaffected by gp91phox-containing NADPH oxidase.
Touyz RM, Mercure C, …, Lochard N, Reudelhuber TL
Hypertension 2005 Apr 45(4):530-7 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Morag Young
Evaluated 16 Jan 2006

Evidence for abnormal left ventricular structure and function in normotensive individuals with familial hyperaldosteronism type I.
Stowasser M, Sharman J, …, Cowley D, Marwick TH
J Clin Endocrinol Metab 2005 Sep 90(9):5070-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Morag Young
Evaluated 13 Jan 2006

Conditional mineralocorticoid receptor expression in the heart leads to life-threatening arrhythmias.
Ouvrard-Pascaud A, Sainte-Marie Y, …, Escoubet B, Jaisser F
Circulation 2005 Jun 14 111(23):3025-33 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Morag Young
Evaluated 9 Jan 2006

Aldosterone stimulates matrix metalloproteinases and reactive oxygen species in adult rat ventricular cardiomyocytes.
Rude MK, Duhaney TA, …, Siwik DA, Sam F
Hypertension 2005 Sep 46(3):555-61 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Morag Young
Evaluated 5 Jan 2006

Aldosterone induces myocyte apoptosis in the heart and skeletal muscles of rats in vivo.
Burniston JG, Saini A, Tan LB, Goldspink DF
J Mol Cell Cardiol 2005 Aug 39(2):395-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Morag Young
Evaluated 4 Jan 2006

Kidney function in mice lacking aldosterone.
Makhanova N, Lee G, …, Kim HS, Smithies O
Am J Physiol Renal Physiol 2006 Jan 290(1):F61-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Morag Young
Evaluated 4 Oct 2005

Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11 beta-hydroxysteroid dehydrogenase type 1.
Bujalska IJ, Draper N, …, Walker EA, Stewart PM
J Mol Endocrinol 2005 Jun 34(3):675-84 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Morag Young / Elise Gomez-Sanchez
Evaluated 21 Sep 2005

Human mineralocorticoid receptor expression renders cells responsive for nongenotropic aldosterone actions.
Grossmann C, Benesic A, …, Gassner B, Gekle M
Mol Endocrinol 2005 Jul 19(7):1697-710 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Elise Gomez-Sanchez / Morag Young
Evaluated 21 Sep 2005

Aldosterone increases plasminogen activator inhibitor-1 synthesis in rat cardiomyocytes.
Chun TY, Pratt JH
Mol Cell Endocrinol 2005 Jul 15 239(1-2):55-61 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Morag Young
Evaluated 20 Sep 2005

Possible contributions of reactive oxygen species and mitogen-activated protein kinase to renal injury in aldosterone/salt-induced hypertensive rats.
Nishiyama A, Yao L, …, Kohno M, Abe Y
Hypertension 2004 Apr 43(4):841-8 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Morag Young
Evaluated 20 Sep 2005

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