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Kim Lewis
Department of Biology, Northeastern University, Boston, United States of America

Faculty Member: Pharmacology & Drug Discovery > Antimicrobial Agents [ since 28 July 2006 ]
[ Evaluations ]
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Evaluations

The ABC-type multidrug resistance transporter LmrCD is responsible for an extrusion-based mechanism of bile acid resistance in Lactococcus lactis.
Zaidi AH, Bakkes PJ, …, Kuipers OP, Driessen AJ
J Bacteriol 2008 Nov 190(22):7357-66 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kim Lewis with Danuta Tomkiewicz
Evaluated 16 Dec 2008

The potential of desferrioxamine-gallium as an anti-Pseudomonas therapeutic agent.
Banin E, Lozinski A, …, Greenberg EP, Banin E
Proc Natl Acad Sci U S A 2008 Oct 28 105(43):16761-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kim Lewis with Lawrence R. Mulcahy
Evaluated 10 Nov 2008

The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis.
Rao SP, Alonso S, …, Dick T, Pethe K
Proc Natl Acad Sci U S A 2008 Aug 19 105(33):11945-50 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kim Lewis with Lawrence R. Mulcahy
Evaluated 10 Oct 2008

Bacteremia associated with toothbrushing and dental extraction.
Lockhart PB, Brennan MT, …, Paster BJ, Bahrani-Mougeot FK
Circulation 2008 Jun 17 117(24):3118-25 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kim Lewis with Lawrence Mulcahy
Evaluated 25 Jul 2008


In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen.
Plouffe D, Brinker A, …, Zhou Y, Winzeler EA
Proc Natl Acad Sci U S A 2008 Jul 1 105:9059-9064 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Paul Roepe / Thomas Kodadek / Kim Lewis
Evaluated 7 Jul 2008

Persistence of Borrelia burgdorferi following antibiotic treatment in mice.
Hodzic E, Feng S, …, Freet KJ, Barthold SW
Antimicrob Agents Chemother 2008 May 52(5):1728-36 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kim Lewis
Evaluated 12 May 2008

Transferable resistance to aminoglycosides by methylation of G1405 in 16S rRNA and to hydrophilic fluoroquinolones by QepA-mediated efflux in Escherichia coli.
Périchon B, Courvalin P, Galimand M
Antimicrob Agents Chemother 2007 Jul 51(7):2464-9 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Kim Lewis
Evaluated 15 Nov 2007

High-throughput screens for small-molecule inhibitors of Pseudomonas aeruginosa biofilm development.
Junker LM, Clardy J
Antimicrob Agents Chemother 2007 Oct 51(10):3582-90 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kim Lewis
Evaluated 15 Nov 2007

Role of a qnr-like gene in the intrinsic resistance of Enterococcus faecalis to fluoroquinolones.
Arsène S, Leclercq R
Antimicrob Agents Chemother 2007 Sep 51(9):3254-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kim Lewis
Evaluated 15 Nov 2007

Resistance mechanisms of multiresistant Pseudomonas aeruginosa strains from Germany and correlation with hypermutation.
Henrichfreise B, Wiegand I, Pfister W, Wiedemann B
Antimicrob Agents Chemother 2007 Nov 51(11):4062-70 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kim Lewis
Evaluated 13 Nov 2007

Tracking the in vivo evolution of multidrug resistance in Staphylococcus aureus by whole-genome sequencing.
Mwangi MM, Wu SW, …, Siggia ED, Tomasz A
Proc Natl Acad Sci U S A 2007 May 29 104(22):9451-6 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jeffrey Thorne / Kim Lewis
Evaluated 10 Aug 2007


Effect of anaerobic growth on quinolone lethality with Escherichia coli.
Malik M, Hussain S, Drlica K
Antimicrob Agents Chemother 2007 Jan 51(1):28-34 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Kim Lewis
Evaluated 19 Mar 2007

Novel bacterial acetyl coenzyme A carboxylase inhibitors with antibiotic efficacy in vivo.
Freiberg C, Pohlmann J, …, Häbich D, Ziegelbauer K
Antimicrob Agents Chemother 2006 Aug 50(8):2707-12 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Lynn Silver / David Payne / Kim Lewis
Evaluated 19 Mar 2007

Mechanisms of uropathogenic Escherichia coli persistence and eradication from the urinary tract.
Mysorekar IU, Hultgren SJ
Proc Natl Acad Sci U S A 2006 Sep 19 103(38):14170-5 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Kim Lewis
Evaluated 20 Feb 2007

Intracellular accumulation of linezolid in Escherichia coli, Citrobacter freundii and Enterobacter aerogenes: role of enhanced efflux pump activity and inactivation.
Schumacher A, Trittler R, …, Pagès JM, Kern WV
J Antimicrob Chemother 2007 Jun 59(6):1261-4 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Kim Lewis
Evaluated 24 Oct 2006

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